Yes, and this goes for all the Disney comics
With a small exception at the bottom. And tagging guidance
The comics are clearly considered on topic as we already have one well received and one positively received question on the topic. We even have a well received question on Mickey Mouse's comic adventures.
Well now that we've determined they were accepted in the past, lets compare them against some policies.
Anthropomorphic animals does not a fantasy make
The Donald Duck adventures seem to clearly break our requirement for what make something on-topic. Considering that although they are anthropomorphic animals, the adventures and themes seem to branch past our every day world into the Science Fictional and Fantastical world. That ticks the box set in this meta
This however fails Valorum's test for talking animals.
That said, we would consider talking animals to be part of a fantasy if:
- They had been uplifted in some way (either by technology or magic)
- Their speaking was somehow fantastical to the other characters.
Meta answer by Valorum
However, while Donald Duck and co's speaking is not "somehow fantastical to the other characters", the adventures they carry out overrules this meta.
Another meta discussing children's literature has most of it deemed off-topic unless some invented creature and creative fantasy exists.
As far as the other concern that will no doubt be raised, of comic-themed cartoons, I think those should be allowed, for now. It's not the best fit, but as almost all comic book heros [sic] are either mutants, genetically engineered, aliens, robots, or people with some futuristic technology, all of which would easily be covered in this site, I say it's on topic
Meta answer by Pearson
There are other characters and events in the series which fit the requirements laid out in the snippet above. With truly fantastical acts and such occurring (such as swimming through gold coins, etc.)
All that being said. The Donald Duck comics seem to be clearly on-topic. As for the rest of the Disney comics, some of the earlier ones may be less on-topic than others.
So as a final conclusion, as long as the questions asked are about Science fictional or fantastical elements portrayed in the comics, they're on topic.
For a few examples our recent questions would be deemed on topic, however asking "What model is Donald's house boat base on?" Would be off-topic and closed as such.
I suggest we use a general universe tag for these, my recommendation would be disney (which already exists), we should then have disney-comics on all the comics specific questions, further down from that the relevant character starring in the comic in question should be added. E.g. in the case of the question donald-duck